Adamas Pharmaceuticals Presents Positive Phase 2/3 Results for ADS-5102

SYDNEY, AUSTRALIA AND EMERYVILLE, CALIF., JUNE 18, 2013 – Adamas Pharmaceuticals,
Inc. presented final results today from a Phase 2/3 clinical trial of ADS-5102 (amantadine HCl extended
release) capsules demonstrating a statistically significant improvement in levodopa-induced dyskinesia
(LID) as measured by change from baseline at week 8 versus placebo in the Unified Dyskinesia Rating
Scale (UDysRS).

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Takeda to acquire Inviragen Inc

Osaka, Japan, May 8, 2013, Deerfield, IL and Fort Collins, CO, U.S.A., May 7, 2013 – Takeda
Pharmaceutical Company Limited (“Takeda”) and Inviragen, Inc. (“Inviragen”) jointly announced today that
Takeda, its wholly owned subsidiary Takeda America Holdings, Inc., and Inviragen, Inc. have entered into a
definitive agreement for Takeda to acquire Inviragen for an upfront payment of US$35 million, and future
payments of up to US$215 million linked to the progress of clinical development and achievement of key
commercial milestones.

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TriReme Announces Signing of a master Distribution Agreement

PLEASANTON, Calif. and SINGAPORE, March 26, 2013 /PRNewswire/ — TriReme Medical, Inc. and its
affiliates (TriReme) announced today that it has signed a comprehensive agreement with Weihai Weigao
Medical Devices, Ltd for the distribution of its products in the People’s Republic of China. Weigao will act
as TriReme’s master distributor by selling TriReme products directly to hospitals as well as connecting
TriReme products into its vast nationwide distribution network. This agreement complements TriReme’s
strategy of focusing on Asia, the fastest growing market in interventional cardiology.

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Ezion awarded a letter of intent from a south east asian state-linked corporation

The Board of Directors of Ezion Holdings Limited (the “Company” or “Group”) is pleased to
announce that the Group has been awarded a letter of intent from a South East Asian Statelinked corporation for the charter of one unit of Liftboat over a 4 year period with an approximate
contract value of up to US$ 116.8 million.

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RAMP Enables Automated Contextual Videos With Launch of MetaQ

One of the main things content providers can do to create rich user experiences is present
contextualized content that relates to the underlying article or video. This is why so many
content sites have “Read More,” “You Might Also Enjoy” and “Also View” type sections. They
help content providers increase users’ time spent (which drives monetization), build loyalty
and create competitive barriers

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